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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Tuberculosis (Edinb). 2011 Dec 21;92(2):160–165. doi: 10.1016/j.tube.2011.11.007

Table 2.

Results from three aerosol exposures with ultra-low doses of MTB*

Aerosol Exposure Group Starting inoculum OD × 10-4 Pre-nebulizer (CFU/mL) × 104 Post-nebulizer (CFU/mL) × 104 Presented Dose (CFU/ mouse) Time of necropsy (weeks) Infected/Total Mice (%)
E 2.5 3.05 0.10 1.1 5 10/28 (36%)
F 0.8 0.35 0.30 1.6 3 5/14 (36%)
G 10 33 10.6 11.0 4 19/20 (95%)
*

Exposures were conducted as described in Table 1. The proportion of mice infected was based on lung cultures at 3-5 weeks after exposure. CFU data from these exposures are shown in Figure 2.