Cells cultured in BME displayed different organizational phenotypes, shown by confocal microscopy (A; red-TOPRO3 nuclear stain, green-laminin V; scale bars represent 50 µm). Organizations of cells were categorized into five classifications as described in the text with examples shown in A. Confocal images of structures for 10A, 10A.ErbB2, and 231 cells were categorized and differences existed between the cell populations (p < 2e-16) (B), with correspondence analysis revealing the most compelling associations (C).