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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Brain Behav Immun. 2011 Nov 12;26(3):371–382. doi: 10.1016/j.bbi.2011.11.002

Figure 1.

Figure 1

Splenic macrophages from mice exposed to the SDR stressor kill more E. coli and produce more peroxynitrite than macrophages from non-stressed control mice. Spleen mass (Fig 1A), the number of splenic monocytes/macrophages (Fig. 1B), and the number of splenic neutrophils (Fig. 1C) were increased in conventional mice exposed to the SDR stressor (*p<0.05 vs. HCC Control). Exposure to the SDR stressor did not affect the number of splenic lymphocytes (Fig. 1D). The number of E. coli remaining alive within splenic macrophages from SDR stressor-exposed mice was significantly lower than the number remaining alive within macrophages from non-stressed HCC Control mice (*p<0.05 vs. HCC Control at 90 min) (Fig. 1E). Splenic macrophages from mice exposed to the SDR stressor produce significantly higher levels of peroxynitrite after stimulation in comparison to levels produced by cells from nonstressed HCC Control mice (*p<.05 vs. HCC Control at 60, 75, and 90 min) (Fig. 1F). Values are means ± SE [n=3 HCC and 3 SDR].