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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: J Immunol. 2012 Jan 30;188(5):2146–2155. doi: 10.4049/jimmunol.1004120

Figure 1. Targeted DCs migrate through the dermis in steady state and inflamed skin.

Figure 1

1μg IgG2a control or anti-DEC-205 mAb were injected intradermally into the ears of C57BL/6 mice. The injection site was then topically treated with imiquimod cream or left untreated (n.t.). Four days after injection, dermal sheets were prepared and fixed. Targeted cells were detected by anti-rat IgG / Alexa Fluor 594™. Dermal lymph vessels were revealed by anti-LYVE-1 antibody, specific for lymphatic endothelial cells. Scale bar represents 100μm. Results are representative of two independent experiments.

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