Table 3.
Gene contents of pathogenic and non-pathogenic extracellular bacteria 604 extracellular bacterial genomes were examined for their average proteome sizes, average GC contents, and gene contents.
| Extracellular pathogens (237 genomes) | Extracellular non-pathogens (367 genomes) | p-Value (Mann–Whitney) | |
|---|---|---|---|
| A | |||
| Mean proteome size (codons) | 1139797 | 1202806 | ns |
| Mean GC content | 49% | 51% | 0.045 |
| Percentage that lack mutM | 24 | 24 | – |
| Percentage that lack mutY | 42 | 72 | – |
| Percentage that lack mutL | 31 | 31 | – |
| Percentage that lack mutS | 25 | 20 | – |
| Host associated extracellular pathogens (82 genomes) | Other extracellular bacteria (522 genomes) | p-Value (Mann–Whitney) | |
| B | |||
| Mean proteome size (codons) | 1094197 | 1198376 | ns |
| Mean GC content | 50% | 50% | No difference in the means |
| Percentage that lack mutM | 22 | 25 | – |
| Percentage that lack mutY | 46 | 64 | – |
| Percentage that lack mutL | 30 | 31 | – |
| Percentage that lack mutS | 20 | 21 | – |
| Intracellular bacteria (95 genomes) | Extracellular bacteria (604 genomes) | p-Value (Mann–Whitney) | |
| C | |||
| Mean proteome size (number of codons) | 342246 | 1183493 | 2.0E–50 |
| Mean GC content | 34% | 50% | 2.6E–29 |
| Percentage that lack mutM | 46 | 25 | – |
| Percentage that lack mutY | 72 | 61 | – |
| Percentage that lack mutL | 40 | 31 | – |
| Percentage that lack mutS | 44 | 23 | – |
(A) Pathogenic (opportunistic and host associated) extracellular bacteria were compared with non-pathogenic extracellular bacteria; (B) host associated pathogenic extracellular bacteria were compared with all other extracellular bacteria; (C) Intracellular bacteria were compared with extracellular bacteria. “ns” denotes not significant.