Skip to main content
. Author manuscript; available in PMC: 2013 Feb 5.
Published in final edited form as: Chem Biol Interact. 2011 Dec 24;195(3):189–198. doi: 10.1016/j.cbi.2011.12.006

Figure 5.

Figure 5

Chlorpyrifos oxon challenge. A) plasma AChE activity; B) plasma BChE activity; C) plasma carboxylesterase activity; D) body temperature. Mice were challenged with 14 mg/kg chlorpyrifos oxon (CPO) transdermally (n=6 per genotype). Points are shown ± std dev. Wild-type mice, ES1+/+, are represented by white bars and white squares. ES1−/− mice are represented by black bars and black squares. At 24 h the wild-type mice (ES1+/+) were either moribund (n=4) or dead (n=2) while the ES1−/− mice had no toxic signs. In the body temperature panel, measurements marked with an “a” are significantly different from those marked with a “b” based on a two tailed t-test p≤0.05.