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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: J Am Coll Surg. 2012 Jan 5;214(3):328–337. doi: 10.1016/j.jamcollsurg.2011.11.006

Figure 6.

Figure 6

IR-813 and Oregon Green-paclitaxel dual-encapsulated expansile nanoparticles: In vivo NIR imaging confirmed migration of the NIR-OGpax-eNP to a specific draining regional LN. Shown are NIR fluorescence (a) and pseudocolored (red) merged images(b) of the draining and nearby LN. Scale bar = 0.5 cm. Fluorescent microscopy confirmed eNP-mediated delivery of paclitaxel chemotherapy within the LN on histologic analysis. The following images are shown: (c) white light, (d) NIR fluorescence of IR-813 (red), (e) Oregon Green fluorescence of encapsulated paclitaxel (green), and (f) pseudocolored merged images. NIR-OGpax-eNP are visualized within an afferent lymphatic vessel (arrow). Scale bar = 200 µm.