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. Author manuscript; available in PMC: 2013 Feb 17.
Published in final edited form as: Circ Res. 2012 Jan 5;110(4):551–559. doi: 10.1161/CIRCRESAHA.111.255927

Figure 1. LR asymmetry in pattern formation by vascular mesenchymal cells.

Figure 1

Phase contrast microscopy of VMCs on (A) conventional plastic substrate at confluence and (B) FN/PEG substrates (interfaces identified by black titanium lines) showing preferential attachment to FN domain immediately after plating. Scale bar, 300 μm and 200 μm (inset). After 10-14 days, development of regularly spaced aggregates (C) in a labyrinthine configuration and (D) in a stripe pattern along principal diagonal axis in bright field (multicellular ridges stained with hematoxylin). Insets: higher magnification images of multicellular aggregates. Scale bar, 2 mm and 300 μm (inset).