Effect of aging on levels of free and protein-bound glutathione in different prostate lobes of the rat. Rats were sacrificed at 4, 12, 18 and 24 months of age and prostate lobes (AL, anterior; VL, ventral; DL, dorsolateral) were removed and analyzed for free glutathione (A) and protein-bound glutathione (B) content as described in text. Points and error bars represent mean ± SEM (n=3). Asterisks reflect statistical significance compared to the young group (P<0.05).