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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Biochim Biophys Acta. 2011 Dec 9;1819(3-4):313–321. doi: 10.1016/j.bbagrm.2011.11.002

Fig. 2.

Fig. 2

Model of new CENP-A deposition and maturation during G1 in animals. During mitotic exit, centromeric chromatin is not competent for CENP-A loading until Mis18 and M18BP1KNL-2 license centromeric chromatin. Two HJURPScm3 molecules deposit newly synthesized CENP-A into the DNA. In mid/late G1, the RSF complex accumulates at centromeres and is implicated in stabilizing new CENP-A, as are MgcRacGAP, ECT2, and Cdc42, which are proposed to further stabilize the newly deposited pool of CENP-A nucleosomes.