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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Neuroimage. 2011 Dec 6;60(1):279–289. doi: 10.1016/j.neuroimage.2011.11.081

Figure 3.

Figure 3

An inaccurate assumption of the flow-volume coupling constant α would result in a systematic error. Here the effect of different underlying physiological values of this coupling were investigated where a solid line represents α=0.2 and the dashed line α=0.4. A minimal shift in the dashed line with respect to the solid line would reflect lower sensitivity to the assumed value of α. Physiological variability is not included in these simulations and haematocrit, oxygen extraction fraction and blood volume were assumed to be 0.45, 0.4, 0.05, respectively.