Table 1.
Baseline characteristics.
| Age, mean ± SD | 63 ± 14 |
|
| |
| Male, n (%) | 29 (45) |
| Ethnicity, n (%) | |
| Caucasian | 37 (57) |
| African-American | 21 (32) |
| Hispanic | 4 (6) |
| Asian | 3 (5) |
|
| |
| NIHSS, median (range) | |
| Pre-tPA | 13 (3–25) |
| % of patients with ≥ 10 | 80 |
| Pre-Argatroban | 13 (3–22) |
| % of patients with ≥ 10 | 76 |
|
| |
| Past Medical History, n (%) | |
| Hypertension | 45 (69) |
| Hyperlipidemia | 20 (31) |
| Atrial Fibrillation | 20 (31) |
| Diabetes Mellitus | 19 (29) |
| Coronary Artery Disease | 16 (25) |
| Prior stroke/TIA | 10 (15) |
| Congestive Heart Failure | 9 (14) |
|
| |
| Antithrombotic medications at presentation, n (%) | |
| Aspirin | 18 (28) |
| Clopidogrel | 3 (5) |
| Warfarin | 10 (15) |
| Total | 30 (46) |
|
| |
| Occluded Vessel, n (%) | |
| MCA | 59 (90) |
| Proximal | 39 (66) |
| Distal | 20 (34) |
| Terminal ICA | 5 (8) |
| Vertebral | 1 (2) |
|
| |
| Vessel Imaging Modality, n (%) | |
| Transcranial Doppler | 48 (74) |
| CT-Angiogram | 17 (26) |
|
| |
| Baseline TIBI score (TCD patients only), mean ± SD | 2 ± 1 |
|
| |
| ASPECTS score, median (range) | 10 (4–10) |
|
| |
| Median (IQR) time from symptom onset to tPA bolus (min) | 128 (94,170) |