TABLE 5.
Relationships between Retinal Vessel Caliber Indices and Causes of Death during Follow-Up among 304 Study Participants in the Longitudinal Study of Ocular Complications of AIDS
| Quartile | ||||
|---|---|---|---|---|
| 1 | 2 | 3 | 4 | |
| Number of deathsa | ||||
| CRAE | 78 | 81 | 66 | 79 |
| CRVE | 64 | 72 | 77 | 91 |
| AVR | 96 | 73 | 76 | 59 |
| Number of participants for whom death certificates were available | ||||
| CRAE | 30 | 22 | 23 | 17 |
| CRVE | 20 | 20 | 24 | 28 |
| AVR | 36 | 28 | 18 | 10 |
| Attributed causes of, or contributors to, death | ||||
| Diseases characterized by vasculopathyb | ||||
| Cardiovascular disease | ||||
| CRAE | 4 | 2 | 0 | 0 |
| CRVE | 2 | 2 | 2 | 0 |
| AVR | 3 | 3 | 0 | 0 |
| Renal disease | ||||
| CRAE | 1 | 0 | 1 | 1 |
| CRVE | 1 | 0 | 0 | 2 |
| AVR | 1 | 0 | 2 | 0 |
| Stroke | ||||
| CRAE | 1 | 1 | 0 | 0 |
| CRVE | 0 | 0 | 2 | 0 |
| AVR | 1 | 1 | 0 | 0 |
| Liver disease | ||||
| CRAE | 4 | 0 | 0 | 3 |
| CRVE | 3 | 0 | 2 | 2 |
| AVR | 4 | 1 | 2 | 0 |
| Other specified diseasesc | ||||
| CRAE | 4 | 3 | 2 | 4 |
| CRVE | 3 | 4 | 3 | 3 |
| AVR | 5 | 4 | 1 | 3 |
| AIDS-related opportunistic infection or malignancy | ||||
| CRAE | 9 | 6 | 7 | 4 |
| CRVE | 7 | 5 | 5 | 9 |
| AVR | 9 | 8 | 5 | 4 |
| AIDS-related, not otherwise specified | ||||
| CRAE | 7 | 9 | 11 | 5 |
| CRVE | 4 | 9 | 7 | 12 |
| AVR | 13 | 9 | 7 | 3 |
| Trauma | ||||
| CRAE | 0 | 1 | 2 | 0 |
| CRVE | 0 | 0 | 3 | 0 |
| AVR | 0 | 2 | 1 | 0 |
AVR=arteriole:venule ratio
CRAE=central retinal arteriolar equivalent
CRVE=central retinal venular equivalent
a
P-values comparing quartiles are 0.59, 0.77, and 0.81 for CRAE, CRVE, and AVR respectively.
b
P-values for the comparison of diseases characterized by vasculopathy vs. other causes are 0.08, 0.54, and 0.31 for CRAE, CRVE and AVR, respectively.
c
Includes organ diseases other than those listed in the table, plus sepsis and shock.