Fig. 6.
ACh-induced dilation in young (A) and old (B) SFA pressurized to 90 or 130 cmH2O for 4 h. Vasodilator responses were assessed in the absence of enzyme inhibitors, in the presence of 300 µM l-NNA, or in the presence of l-NNA + 5 µM Indo. B, baseline diameter before the 1st dose of ACh. Values are means ± SE; n = 8–9 rats/group. Significantly different from 1p90 and 2p130, P ≤ 0.05.