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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Pflugers Arch. 2011 Nov 19;463(1):139–160. doi: 10.1007/s00424-011-1053-z

Table 2.

Effect of partial sleep deprivation on weight regulation

Outcome measure Effect reported No effect reported Inverse effect
reported
Increased hunger
 Total number of studies 5 [14, 99, 117, 144, 162] 6 [11, 122, 145,
146, 170, 194]
 Total number of patients 53
(50 M, 3 F)
95
(53 M, 42 F)
 Average TIB duration (range) 4.6 h
(4 h to 5.5 h)
4.3 h
(3 h to 5.75 h)
 Average duration of sleep restriction (range) 4 nights
(1–14 nights)
3 nights
(1–5 nights)
 Number of studies that controlled food intake prior to hunger assessment 5 [14, 99, 117, 144, 162] 4 [11, 122, 146, 170]
Increased caloric intake
 Total number of studies 6 [11, 14, 104, 116, 170, 179]. 1 [146]
 Total number of subjects 85
(49 M, 36 F)
15
(15 M)
 Average TIB duration (range) 4.9 h
(4 h–5.75 h)
4.25 h
 Average duration of sleep restriction (range) 5.3 nights
(1–14)
2 nights
Increased weight or adiposity
 Total number of studies 2 [11, 117] 1 [116]
 Total number of patients 24
(17 F, 7 M)
11
(6 M, 5 F)
 Average TIB duration (range) 5.6 h
(5.5 h–5.75 h)
5.5 h
 Average duration of sleep restriction (range) 9 nights
(4 to 14 nights)
14 nights
Decreased leptin levels
 Total number of studies 3 [62, 161, 162] 5 [99, 116, 117,
144, 146]
4[11, 122, 154, 194]
 Total number of patients 31
31 M
55
(47 M, 8 F)
180
(84 M, 96 F)
 Average TIB duration (range) 4 h
(4–4)
4.95 h
(4.25–5.5)
4 h
(3–5)
 Average duration of sleep restriction (range) 5 nights
(2–7)
6.6 nights
(1–14)
3.5 nights
(1–5)
 Number of studies that controlled food prior or during blood sampling 3 [62, 161, 162] 3 [99, 117, 144] 2 [122, 194]
 Average range of BMI 19.5–26.5 23.2–28.6 18.6–40.3
Increased ghrelin levels
 Total number of studies 3 [117, 144, 162] 4 [11, 99, 116, 146]
 Total number of patients 29
(26 M, 3 F)
50
(31 M, 19 F)
 Average TIB duration 4.6 h
(4–5.5)
5.1 h
(4.25–5.75)
 Average duration of sleep restriction 5.6 nights
(1–14)
5.5 nights
(2–14)
 Number of studies that controlled food prior or during blood sampling 3 [117, 144, 162] 1 [99]
 Average range of BMI 22.2–27.6 22–32.8

TIB time in bed