Table 1.
Newly identified proteins in the post-I/R cardiac ECM.
| Accession number |
Name | Currently known functions |
|---|---|---|
| AGRIN_HUMAN | Agrin | Aggregation of acetylcholine receptors |
| ASPN_HUMAN | Asporin | Negative regulator of chondrogenesis |
| CILP1_HUMAN | Cartilage intermediate layer protein 1 | Cartilage scaffolding |
| CO4A2_HUMAN | Collagen alpha-2 (IV) | Structural integrity of basement membrane |
| COCA1_HUMAN | Collagen alpha-1 (XII) | Mediates interaction between collagen fibrils and other extracellular matrix proteins |
| COEA1_HUMAN | Collagen alpha-1 (XIV) | Integrating collagen bundles |
| EMIL1_HUMAN | EMILIN-1 | Elastogenesis and maintenance of vascular cell morphology |
| MATN4_HUMAN | Matrilin-4 | Formation of filamentous networks |
| NID1_HUMAN | Nidogen-1 | Connects network of collagens and laminins |
| PODN_HUMAN | Podocan | Growth and migration of cells in cardiovascular tissues |
| PRELP_HUMAN | Prolargin | Anchoring basement membranes to underlying connective tissue |
| SPON1_HUMAN | Spondin-1 | Axon outgrowth and cell migration during development |
| TENX_HUMAN | Tenascin-X | Matrix maturation during wound healing |
| TETN_HUMAN | Tetranectin | Fibrinolysys and proteolysis during tissue remodeling |
| TINAL_HUMAN | Tubulointerstitial nephritis antigen-like | Promotes cell adhesion and spreading |