Table 9.
MicroRNA | Target IL-17 Cytokines and Receptors | Target CVD Molecules | Target Inflammation Molecules | Target Cancer-Related Molecules |
---|---|---|---|---|
MiR-146 | IL-17A | TRAF6/IRAK-1(87), IRF-5(88) | ||
MiR-17 | IL-17F | p21, Jak1(89) | AML-1(90) | |
MiR-20a | IL-17F | VEGF(91) | AML-1(92) | TGFBR2(90) |
MiR-20b | IL-17F | VEGF(92) | ||
MiR-155 | IL-17RB | AT1R(93) | MMP-3(94), PU.1(95), TAB2(96) | |
MiR-221 | IL-17RB | c-Kit(97), eNOS(98) | ||
MiR-222 | IL-17RB | c-Kit(97), eNOS(98) | ||
MiR-21 | IL-17RD | RECK, TIMP3(99), TPM1(100), PTEN(101), PDCD4(102) |