Table 3.
Pathway | P Value | Genes |
---|---|---|
Circadian rhythms | 0.04 | Dbp↓, Arntl↑, Per1↑, Per2↓, Bhlhb2↓, Bhlhb3↓, Nr1d1↓, Npas2↑, Tef↓, Cry1↑ |
Oxidative phosphorylation | 0.03 | mt-Nu5m↑, mt-Cox2↑, mt-Atp8↑, mt-Cox1↑, mt-Nu3m↓, mt-Nu4m↑, mt-Atp6↓, mt-Cyb↑, mt-Cox3↓, mt-Nu2m↑, Atp5e↓, Cox17↓, Atp5 g3↓, Ndufs2↓, Uqcrh↑, Cox7b↓, Cox6a2↓, Cox8 h↓, Cox5a↓, Ndufb7↑, Atp5o↓, Atp5f1↑, Sdhc↑, Uqcrc1↑, Cox4i1↓, Ndufa10↓ |
↑ and ↓ denote up- and downregulated, respectively, in SHR-Cd36 transgenic vs. SHR controls; P value is Benjamini corrected.