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List of top IPA canonical pathways
| Pathway | P Value | Genes |
|---|---|---|
| Circadian rhythms | 1.9E-08 | Arntl↑, Per1↑, Per2↓, Bhlhb2↓, Bhlhb3↓ |
| VDR/RXR activation | 9.8E-05 | Klf4↑, Cebpb↑, Cdkn1a↑, Wt1↑, Igfbp3↑ |
| IGF1 signaling | 1.9E-04 | Fos↑, Jun↑, Igf1r↑, Igfbp4↓, Igfbp3↑ |
| HMGB1 signaling | 2.0E-04 | Rhob↑, Fos↑, Jun↑, Plat↑, Rhoj↑ |
↑ and ↓ denote up- and downregulated, respectively, in SHR-Cd36 transgenic vs. SHR controls; P value is Benjamini corrected.
