Fig. 1.

Mature sequences and primary transcripts of the miR-29 family. A: mature sequences of the miR-29 family members are conserved in human (hsa-), mouse (mmu-), and rat (rno-), and share identical seed regions. Nucleotides that differ among the miR-29 family members are shown in red. B: primary transcripts of the miR-29 gene clusters in human. Exons and introns are shown as vertical boxes and horizontal lines, respectively. The hairpins indicate the locations of the sequences encoding precursors of miR-29s. Numbers indicate the nucleotide length of each exon or intron.