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. Author manuscript; available in PMC: 2012 Feb 28.
Published in final edited form as: Eur J Immunol. 2010 Oct;40(10):2816–2829. doi: 10.1002/eji.201040384

Figure 5.

Figure 5

Response to infection with L. (V.) panamensis of WT and IL-13 or IL-4Rα-deficient mice. Cytokine responses of WT, IL-13- or IL-4Rα-deficient BALB/c mice at different times post-infection, as indicated. ELISA analyses for cytokines were performed on supernatants of spleen-derived lymphocytic cells stimulated with Con A or pLAg (as indicated in the Materials and methods section). Data show mean ± SEM. *(IL-13 KO) and +(IL-4Rα KO) indicate p < 0.05 by Student’s T-test. Similar results were obtained in another independent experiment at 3.5 wk. The IL-4 production by lymphocytes of IL-4Rα-deficient mice is not shown. However, consistent with the previous observations [68], IL-4 levels were found to be >300 pg/mL at all time points.