Table 2.
Cell Population | WT BALB/c
|
Ratio: Infected/naïve | IL-13-deficient BALB/c
|
Ratio: Infected/naïve | ||
---|---|---|---|---|---|---|
Naïve | Infected | Naïve | Infected | |||
CD3e+ | 1.45 ± 0.01 × 106 | 3.69 ± 0.01 × 106 | 2.54 | 1.36 ± 0.01 × 106 | 2.13 ± 0.01 × 106 | 1.57 |
CD4+ | 9.70 ± 0.03 × 105 | 2.66 ± 0.03 × 106 | 2.74 | 9.93 ± 0.06 × 105 | 1.52 ± 0.05 × 106 | 1.53 |
CD8+ | 4.19 ± 0.05 × 105 | 1.05 ± 0.01 × 106 | 2.50 | 3.52 ± 0.01 × 105 | 5.97 ± 0.02 × 105 | 1.70 |
CD19+ | 4.37 ± 0.05 × 105 | 2.77 ± 0.03 × 106 | 6.45 | 2.68 ± 0.01 × 105 | 1.00 ± 0.01 × 106 | 3.73 |
CD11b+ | 2.04 ± 0.01 × 104 | 5.00 ± 0.0 × 104 | 2.45 | 1.68 ± 0.04 × 104 | 4.00 ± 0.22 × 104 | 2.38 |
CD4+FOXP3+ | 1.03 ± 0.02 × 105 | 2.68 ± 0.03 × 105 | 2.60 | 7.26 ± 0.29 × 104 | 1.72 ± 0.03 × 105 | 2.37 |
Values represent the absolute number of LN cells (average of six to ten pooled sets of popliteal and inguinal LN) at 3.5 wk post-infection that are positive for each cell marker (CD4, CD8, CD19, CD3e and CD11b) and FOXP3. Staining was performed in duplicate and the standard deviation for each measurement is presented. The experimental data are representative of two independent experiments.