Table 1.
Federal Motor Carriers Safety Administration (FMCSA) Review of Crash Risk by Medical Disorders (2007-2010)14-18a
| FMCSA Evidence Report Medical Condition (Year) | Increased Crash Risk | Relative Risk (95% Confidence Interval) | No. of Studies With Direct Evidence | Strength of Evidence/Conclusion |
|---|---|---|---|---|
| Diabetes mellitus (2006) | Yes | 1.19 (1.08-1.31) | 13 | Weak |
| Schedule II licit medications (2006) | Cannot determine | 0 | Weak | |
| Cardiovascular disease (2006) | ||||
| Cardiovascular disease | Yes | 1.43 (1.11-1.84) | 8 | Acceptable |
| Hypertension | Yes | Estimate unstable | 2 | Acceptable |
| Seizure disorders (2007) | Yes | 1.13 to 2.16 | 8 | Moderate |
| Obstructive sleep apnea (2007) | Yes | 1.30 to 5.72 | 9 | Strong |
| Renal disease (2007) | Direct: no Indirect: plausible |
2 | Acceptable | |
| Vision (2007) | ||||
| Monocular vision | 4 | Insufficient | ||
| Red-green color deficiencies | 1 | Insufficient | ||
| Visual field loss | Yes | Indeterminate | 12 | Minimally acceptable |
| 240% Reduction in useful field of view | Yes | Indeterminate | 6 | Moderate |
| Cataracts | 4 | Insufficient | ||
| Diplopia | 1 | Insufficient | ||
| Musculoskeletal disease (2007) | ||||
| Amputation of extremity | No | 2 | Minimally acceptable | |
| Inflammatory arthritis | Indeterminate | 3 | Minimally acceptable | |
| Decreased angle of rotation at spine/neck | Indeterminate | 0 | Minimally acceptable | |
| Hearing (2008) | ||||
| Hearing impairment | No | 3 | Acceptable | |
| Vestibular dysfunction | Inconclusive | 1 | Not stated | |
| Psychiatric disease (2008) | ||||
| Psychiatric disease | Inconclusive | 8 | Minimally acceptable | |
| Psychotic disorders | Inconclusive | 4 | Minimally acceptable | |
| Mood disorders | Inconclusive | 3 | Not stated | |
| Anxiety disorders | Inconclusive | 1 | Not stated | |
| Personality disorders | Inconclusive | 3 | Not stated | |
| Benzodiazepine use | Yes | Not provided | 9 | Moderate |
| Antipsychotic use | Inconclusive | 1 | . . . | |
| Antidepressant use | Inconclusive | 7 | Minimally acceptable | |
| Stroke (2009) | Yes | Indeterminate | 3 | Minimally acceptable |
| Parkinson disease (2009) | Yes, for Hoehn and Yahr stages 2 and 3 | Not provided | 3 | Minimally acceptable |
| Multiple sclerosis (2009) | Inconclusive | Indeterminate | 2 | Not stated |
| Traumatic brain injury (2010) | Inconclusive | 1.32 (0.77-2.25) | 5 | Moderate |
a
Inconclusive indicates insufficient evidence to determine whether risk is increased. Indeterminate indicates could not be determined from the available evidence. If inconclusive or insufficient evidence was available, no crash risk could be estimated.