Table 6.
Pd-catalyzed cross-coupling reactions involving 5-membered heterocycles with multiple heteroatomsa
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ArBr (1.0 mmol), amine (1.2 mmol).
65 °C.
NaOt-Bu, dioxane.
K2CO3, t-BuOH, 110 °C.
ArCl.
90 °C.
Pd-catalyzed cross-coupling reactions involving 5-membered heterocycles with multiple heteroatomsa
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ArBr (1.0 mmol), amine (1.2 mmol).
65 °C.
NaOt-Bu, dioxane.
K2CO3, t-BuOH, 110 °C.
ArCl.
90 °C.