Fig. 4.

ZnT-3 KO animals showed higher CSD incidence. Increased CSD propagation rates and frequencies in ZnT-3 KO animals. A: representative traces of repetitive CSD generated by topical KCl applications in WT and ZnT-3 KO. Arrowheads indicate onset of CSD, and recording artifacts generated by reapplication of KCl are denoted by asterisks. B: propagation rates of CSD in WT and ZnT-3 KO. Mean SD propagation rates were determined for each animal from the time offset between CSDs detected with a pair of electrodes. (*P < 0.05; n = 6.) C: inter-CSD intervals were significantly lower of ZnT-3 KO animals. (*P < 0.001; n = 6.)