Table 2.
Myoplasmic [Ca2+]rest (nM) for WT, Het, and Hom mice
| Time point and sex | WT | Het | Hom |
|---|---|---|---|
| Before halothane | |||
| Male | 117 ± 5 (9) | 292 ± 14 (20)*** | 345 ± 19 (15)*** |
| Female | 115 ± 3 (11) | 258 ± 9 (14)*** | 324 ± 16 (10)*** |
| After halothane (20–25 min) | |||
| Male | 117 ± 3 (5) | 1821 ± 66 (10)*** | 2276 ± 228 (10)*** |
| Female | 118 ± 4 (5) | 1125 ± 253 (10)*** | 2067 ± 132 (10)*** |
| After halothane (35–40 min) | |||
| Male | 116 ± 4 (5) | DNS | DNS |
| Female | 117 ± 4 (5) | 1636 ± 63 (10)*** | DNS |
Values are means ± sd; numbers in parentheses indicate number of blocks analyzed. DNS, did not survive.
***
P < 0.001 vs. WT.