Table 3.

Subsarcolemmal accumulation (sSA) of mitochondira and/or amorphous material in 1-yr-old mouse soleus fibers

Genotype and sex	Longitudinal section		Cross section
	Fiber segments occupied by sSA (%)	Fiber length segments occupied by sSA (%)	Fiber occupied by sSA (%)	sSA area (μm2)
WT
Male	34	2.7 ± 4.4	60	22.9 ± 19.0
Hom
Male	56	12.4 ± 15.2	83	46.3 ± 53.8
Female	38	3.14 ± 4.1	67	20.8 ± 17.2

Length and area values are means ± sd. Student's t test: WT vs. Hom male, P = 5.5 × 10⁻⁶; WT vs. Hom female, P = 0.8; Hom male vs. Hom-female P > 7.2 × 10⁻⁶. Longitudinal section: WT: 3 mice, 3 muscles, 50 fiber segments, total 10,100 μm; Hom male: 2 mice, 3 muscles, 51 fiber segments, total 13,700 μm; Hom female: 2 mice, 2 muscles, 39 fiber segments, total 10,500 μm. Cross section: WT: 2 mice, 2 muscles, 97 fiber segments; Hom male: 2 mice, 2 muscles, 106 fiber segments; Hom female: 2 mice, 2 muscles, 99 fiber segments.