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Up-regulation of RANKL following muscle paralysis. Mean ± se expression of RANKL (A) and OPG (B) within the proximal tibia microenvironment adjacent to BTxA-induced calf paralysis and in the contralateral tibia. RANKL was significantly increased at 7 d postparalysis in the BTxA-injected side. OPG expression was unchanged. *P < 0.02 vs. 1 d combined data.
