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. 2012 Mar;26(3):1110–1118. doi: 10.1096/fj.11-196642

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Figure 3. — OPG treatment prevents MPIBL. A) Mean (±se) BV/TV in the left (contralateral) and right (BTxA) tibial metaphysis. BV/TV was reduced in BTxA-treated limbs compared with saline-treated mice, with no difference between the contralateral tibae. BV/TV was significantly increased in experimental right tibia and contralateral left tibiae of the BTxA + OPG group compared with the same tibiae of the saline group. *P = 0.01, ^[212]P = 0.01 vs. corresponding saline group. B) Representative microCT cross-sectional images through the right tibia metaphysis of saline-, BTxA-, and BTxA+OPG-treated mice.