Table 1.
Control (N=20) | DEX (N=32) | P-value | |
---|---|---|---|
Age, m | 2.6 (0.13– 158) | 4.8 (0.16 – 198) | 0.29 |
Weight, Kg | 3.9 (2.6– 99) | 5.3 (2.6 – 83) | 0.23 |
Sex, F (%) | 12 (60) | 11 (34) | 0.13 |
Aristotle Score | 7.3 (4.0– 14.5) | 8.5 (3.0–14.5) | 0.24 |
CICU Stay, d * | 4 (1–16) | 4 (1–20) | 0.59 |
Hospital Stay, d † | 7 (3–19) | 8 (3–45) | 0.63 |
Intraoperative data | |||
CPB Time, min | 79 ± 9 | 93 ± 7 | 0.12 |
Aortic Clamp Time, min | 30 ± 6 | 33 ± 6 | 0.84 |
Circulatory Arrest time, min | 31 ± 6 | 26 ± 4 | 0.57 |
Modified Ultrafiltration, ml/kg | 71 ± 5 | 65 ± 3 | 0.14 |
Dexmedetomidine LD, mcg/kg | 1 ± 0.1 | ||
Dexmedetomidine, mcg/kg/hr | 0.5 | ||
Sufentanyl, mcg/kg/min | 0.33 ± 0.06 | 0.28 ± 0.03 | 0.40 |
Fentanyl, mcg/kg | 25 ± 7 | 20 ± 4 | 0.85 |
Midazolam, mg/kg | 0.33 ± 0.06 | 0.33 ± 0.05 | 0.69 |
Caudal-block, n (%) | 2 (10) | 6 (19) | 0.65 |
Epinephrine, mcg/kg/min | 0.06 ± 0.01 | 0.07 ± 0.01 | 0.92 |
Milrinone, mcg/kg/min | 0.88 ± 0.17 | 0.87 ± 0.17 | 0.85 |
Methylprednisolone, mg/kg | 28 ± 1 | 29 ± 1 | 0.4 |
Magnesium Sulphate, meq/kg | 0.4 ± 0.1 | 0.4 ± 0.1 | 0.4 |
CICU: cardiac intensive care unit; CPB: cardiopulmonary bypass; LD: loading dose
Length of stay from surgery to CICU discharge;
Length of stay from surgery to hospital discharge