Table 1. Cytokines in lung homogenates of B10.A mice infected i.t. with P. brasiliensis Pb 18 yeasts and submitted to gene immunization for 5 months.
Cytokines pg/ml | IL-10 | IFN-γ |
Untreated | 12.18±4.61 | 4.71±1.75 |
pcDNA3 | 10.38±6.53 | 4.73±2.45 |
pP10+pcDNA3 | 18.71±6.10 | 7.64±2.46 |
pP10+pIL-12 | 12.00±2.06 | 7.31±1.37 |
Mice were sacrificed 1 month after the last dose.