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. 2012 Feb 28;6(2):e1527. doi: 10.1371/journal.pntd.0001527

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Venn diagrams representing the number of genes either upregulated (upward facing arrows) or downregulated (downward facing arrows) to parasite (microfilarial Ag; MfAg, top panels) and nonparasite (streptolysin O; SLO, bottom panels) antigens in endemic (pink circles) and expatriate (blue circles) filarial-infected patients. CD4⁺ T cells are shown in the left panels and CD8⁺ T cells are in the right panels. Numbers represent genes that were significantly up-or down-regulated (p<0.001) in comparison to unstimulated cells.