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. 2012 Feb 28;7(2):e32256. doi: 10.1371/journal.pone.0032256

Figure 1. Nitric oxide augments whole-cell barium currents.

Figure 1

A, Raw traces of recorded unpaired barium currents of control (7-NI) neurons and following exposure to NO donor (DEA or SNP, 100 µM each) using the protocol shown above. B, Average I/V curves under conditions indicated. C, Mean peak CaV currents (arrow in A) show NO-dependent augmentation induced by sodium nitroprusside (SNP, 100 µM) or Diethyl ammonium-nonoate (DEA-nonoate, 100 µM), data denote mean±SEM, unpaired observations, Student's t-test, *P<0.05. D, Mean inactivation kinetics (τ) of currents evoked by step depolarisation to −10 mV. E, Boltzmann fit to conductances (G/Gmax) under conditions indicated.