Table 5. Gene ontology (GO) analysis of proteins that were preferentially identified after H2O2 oxidation treatment of cells.
| GO Biological Process | Protein | ||||||
| Translation2.98E−05† | mRNA Processing4.11e−07† | Nuclear mRNA Splicing, via Spliceosome3.36e−08† | Entrez gene | gi | Mass [kDa] | Description | pValue |
| X | X | 6432 | 72534660 | 27.37 | serine/arginine-rich splicing factor 7 isoform 1 | 5.18E−011 | |
| X | X | 4869 | 10835063 | 32.57 | nucleophosmin isoform 1 | 0.00E+000 | |
| X | X | 6434 | 4759098 | 33.67 | transformer-2 protein homolog beta | 2.51E−008 | |
| X | X | 3191 | 52632383 | 64.13 | heterogeneous nuclear ribonucleoprotein L isoform a | 1.17E−009 | |
| X | X | 6428 | 4506901 | 19.33 | serine/arginine-rich splicing factor 3 | 9.06E−047 | |
| X | X | 5093 | 222352151 | 37.50 | poly(rC)-binding protein 1 | 1.98E−036 | |
| X | X | 220988 | 34740329 | 39.59 | heterogeneous nuclear ribonucleoprotein A3 | 2.26E−007 | |
| X | X | 8683 | 4506903 | 25.54 | serine/arginine-rich splicing factor 9 | 4.98E−004 | |
| X | X | 5094 | 14141166 | 38.22 | poly(rC)-binding protein 2 isoform b | 2.55E−013 | |
| X | X | 1207 | 4502891 | 26.22 | methylosome subunit pICln | 8.07E−012 | |
| X | X | 6426 | 5902076 | 27.74 | serine/arginine-rich splicing factor 1 isoform 1 | 1.15E−004 | |
| X | 4841 | 34932414 | 54.23 | non-POU domain-containing octamer-binding protein isoform 1 | 4.44E−006 | ||
| X | 8570 | 154355000 | 73.12 | far upstream element-binding protein 2 | 4.85E−014 | ||
| X | 1984 | 4503545 | 16.83 | eukaryotic translation initiation factor 5A-1 isoform B | 0.00E+000 | ||
| X | 3692 | 4504771 | 26.60 | eukaryotic translation initiation factor 6 isoform a | 4.05E−013 | ||
| X | 2617 | 1.17E+08 | 83.16 | glycyl-tRNA synthetase | 1.89E−018 | ||
| X | 1975 | 50053795 | 69.15 | eukaryotic translation initiation factor 4B | 2.84E−018 | ||
| X | 1938 | 4503483 | 95.34 | elongation factor 2 | 1.42E−102 | ||
| X | 23708 | 46094014 | 68.88 | eukaryotic peptide chain release factor GTP-binding subunit ERF3B | 1.19E−004 | ||
| X | 6176 | 4506669 | 11.51 | 60S acidic ribosomal protein P1 isoform 1 | 5.60E−010 | ||
| X | 6206 | 14277700 | 14.51 | 40S ribosomal protein S12 | 1.29E−010 | ||
| X | 1937 | 4503481 | 50.12 | elongation factor 1-gamma | 9.40E−016 | ||
| X | 3315 | 4504517 | 22.78 | heat shock protein beta-1 | 0.00E+000 | ||
| X | 136319 | 21956645 | 12.89 | myotrophin | 5.60E−018 | ||
| X | 1933 | 4503477 | 24.76 | elongation factor 1-beta | 6.79E−010 | ||
†
The adjusted pValue assigned to the biological process by the WebGestalt GO analysis using the hypergeometric statistical test with a BH multiple test adjustment.