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. 2012 Feb 28;7(2):e32708. doi: 10.1371/journal.pone.0032708

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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The fraction of clones containing missense or stop mutations for cases with each indicated clinical or pathological parameter is shown. All differences between pathological and clinical variables were statistically significant. Specifically: for early PSA recurrence (<2 years post surgery) versus no or late recurrence (p<0.001, chi sq); extracapsular extension (ECE) versus no ECE (p = 0.015, chi sq); seminal vesicle invasion (SVI) versus no SVI (p = 0.027, chi sq); pelvic lymph node metastasis (LN) versus no metastasis (p = 0.027, chi sq); Gleason 5/6 versus 7–10 (p = 0.002, chi sq).