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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Lab Invest. 2011 Dec 12;92(3):437–450. doi: 10.1038/labinvest.2011.192

Figure 3. Epithelial ErbB3 is required for short-term and long-term recovery from DSS-induced colitis.

Figure 3

ErbB3 KOIEI (A, B, C, Di, E, F) or ErbB3 KOIEC (B, Dii) mice and their respective wild-type controls were treated with 3% DSS for 4 or 8 days (A, C, E), or were treated with 3% DSS for 4 days followed by a recovery period of 3 days or 6 weeks on normal water (B, D, F), as indicated; n=7–13. (A, B) Representative H&E sections of colons from the indicated mice. Scale bars, 100 μm. (C, D) Colonic injury scores were quantified by a pathologist blinded to the treatment and group. Bars indicate mean value. (E) Body weight loss during DSS administration; values indicate mean±SD. (F) Body weight loss during the 3 day recovery period following 4 days of DSS administration; values indicate mean±SD.