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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Lab Invest. 2011 Dec 12;92(3):437–450. doi: 10.1038/labinvest.2011.192

Figure 5. Loss of ErbB2 or ErbB3 exacerbates epithelial hyperproliferative response during recovery from DSS-induced colitis.

Figure 5

(A, B) Immunostaining for the proliferative marker Ki67 (brown nuclei) in colonic sections of ErbB2 KOIEC (A), and ErbB3 KOIEI mice (B) and their respective wild-type controls treated with water, DSS for 4 days or DSS followed by a 3 day recovery period, as indicated. Images are representative of 8–12 mice per group. Scale bars, 100 μm. (C, D) The number of Ki67-positive cells per crypt were quantified in a blinded manner. Bars indicate mean values.