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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Lab Invest. 2011 Dec 12;92(3):437–450. doi: 10.1038/labinvest.2011.192

Figure 6. Loss of ErbB2 or ErbB3 increases colonic epithelial apoptosis.

Figure 6

(A, B) Apoptotic cells (arrows) in colon sections were detected by TUNEL staining from wild-type or knockout mice treated with water, DSS for 4 days or DSS followed by a 3 day recovery period, as indicated. Images are representative of 8–12 mice per group. Scale bars, 50 μm. (C, D) The number TUNEL-positive cells per 100 crypts were quantified in a blinded manner. Bars indicate mean values.