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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Am J Emerg Med. 2011 Nov 17;30(8):1336–1346. doi: 10.1016/j.ajem.2011.09.018

Figure 1.

Figure 1

Hemorrhage was induced by withdrawing 50% of the animal’s BV. Hypovolemia was maintained for 1 hour. Small fluid resuscitation was implemented initially by infusion of 3.5% of the BV with HTS, and five minutes after HTS, followed by infusion of 10% of the BV with PolyHSA resuscitation fluids. The resuscitation fluids comprised of three different formulations of PolyHSA at 10 g/dl, namely: PolyHSA24:1 (synthesized at a 24:1 molar ratio of glutaraldehyde to HSA), PolyHSA60:1 (synthesized at a 60:1 molar ratio of glutaraldehyde to HSA), and PolyHSA94:1 (synthesized at a 94:1 molar ratio of glutaraldehyde to HSA). Parameters were analyzed before hemorrhage (Baseline, BL), after hemorrhage (Shock, Sh, 60 min after hemorrhage induction), and at 60 and 90 min after fluid resuscitation (Resuscitation 60 min, R60 and Resuscitation 90 min, R90).