Table I.
Mice distribution.
| Blood | Tissue | C57BL/6 (n122) | ApoE-/- (n126) | PAI-1-/- (n35) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TC | D2 | D6 | D14 | TC | D2 | D6 | D14 | TC | D2 | D6 | D14 | ||
| PAI-1 | u-PA (W/T) | 5 | 10 | 10 | 10 | 5 | 10 | 10 | 10 | ||||
| Plasmin | MCP-1 (W) | 5 | 10 | 10 | 10 | 5 | 12 | 10 | 12 | ||||
| MMP2/9 (W) | 5 | 12 | 10 | 10 | 5 | 11 | 10 | 11 | |||||
|
| |||||||||||||
| Thrombus weight | 15 | 32 | 30 | 30 | 15 | 33 | 30 | 33 | 5 | 10 | 10 | 10 | |
|
| |||||||||||||
| Histology | 5 | 5 | 5 | 5 | 5 | 5 | |||||||
TC: True control or no DVT mice. D2, D6, D14: Days after surgery. PAI-1: Plasminogen activator inhibitor-1. u-PA: Urokinase. MCP-1: Monocyte chemoattractant protein-1. MMP: Matrix metalloproteinase. W/T: Vein wall and thrombus. W: Vein wall. C57BL/6: wild type mice. ApoE-/-: Apolipoprotein E null mice. PAI-1-/-: PAI-1 null mice.