Table 4.
Number of variant carriers in IBD and in non-IBD controls.
| SNP | SNP carriers in IBD | SNP carriers in controls | OR (CI) | P (a) | ||
|---|---|---|---|---|---|---|
| N of subjects | N (%) of variant carriers | N of subjects | N (%) of variant carriers | |||
| 12332979G>T | 283 | 0 (0) | 182 | 1 (0.5) | NA | 0.39 |
| 12333068insC | 283 | 1 (0.4) | 181 | 0 (0) | NA | 0.61 |
| 12333070C>T | 283 | 0 (0) | 181 | 1 (0.6) | NA | 0.39 |
| 12333125A>G | 283 | 58 (20.5) | 182 | 48 (26.4) | 0.72 | 0.14(b), (c) |
| 12333125A>G | 227 | Hom only: 2 (0.9) | 136 | Hom only: 2 (1.5) | 0.60 | 0.63(c) |
| 12333199T>G | 283 | 1 (0.4) | 181 | 0 (0) | NA | 0.61 |
| 12333213G>A | 283 | 0 (0) | 182 | 3 (1.6) | NA | 0.06 |
| 12361272C>T | 281 | 1 (0.4) | 179 | 0 (0) | NA | 0.61 |
| 12361422A>G | 281 | 0 (0) | 179 | 1 (0.6) | NA | 0.39 |
| 12363017A>G | 277 | 1 (0.4) | 167 | 0 (0) | NA | 0.62 |
| 12374014G>T | 280 | 1 (0.4) | 174 | 0 (0) | NA | 0.62 |
| 12374024A>T | 280 | 1 (0.4) | 174 | 0 (0) | NA | 0.62 |
| 12374091C>A | 280 | 1 (0.4) | 174 | 0 (0) | NA | 0.62 |
| 12374110C>T | 280 | 1 (0.4) | 174 | 0 (0) | NA | 0.62 |
| 12374272A>T | 280 | 1 (0.4) | 174 | 1 (0.6) | 0.62 | 0.62 |
| 12374352C>T | 280 | 0 (0) | 174 | 1 (0.4) | NA | 0.38 |
| 12387616G>A | 282 | 1 (0.4) | 179 | 0 (0) | NA | 0.61 |
| 12398613C>T | 281 | 0 (0) | 185 | 1 (0.5) | NA | 0.40 |
| 12415473G>A | 273 | 0 (0) | 175 | 1 (0.6) | NA | 0.39 |
| 12415557C>T | 273 | 63 (23.1) | 175 | 42 (24) | 0.95 | 0.82(b ), (c) |
| 12415557C>T | 213 | Hom only: 3 (1.4) | 137 | Hom only: 4 (2.9) | 0.48 | 0.44(c) |
| 12415581G>A | 273 | 0 (0) | 175 | 1 (0.6) | NA | 0.39 |
| 12415647G>A | 273 | 2 (0.7) | 175 | 0 (0) | NA | 0.37 |
| 12415669C>T | 273 | 0 (0) | 175 | 1 (0.6) | NA | 0.39 |
OR: odds ratio; CI: confidence interval; no.: number; N: absolute number; het: heterozygous; hom: homozygous; NA: not applicable; (a) P values calculated with Fisher's exact test; (b) P value calculated with Chi-Square test; (c)12333125A>G: adjusted for age and sex: P = 0.14 (OR 0.72 C.I. (0.46–1.11)) (het + hom); P = 0.53 (hom. only); 12415557C>T: adjusted for age and sex: P = 0.76 (OR 0.93 C.I. (0.59–1.46)) (het + hom), P = 0.35 (OR 0.7 C.I. (0.33–1.49)) (hom only).