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Overview of H4K20me. (A) Schematic diagram of the different methylation states of histone H4K20; from left to right: unmethylated (H4K20), monomethylated (H4K20me1), dimethylated (H4K20me2), and trimethylated (H4K20me3), with the various mammalian enzymes that perform these post-translational modification. (B) Properties of each of the enzymes that affect H4K20 methylation.
