Table 1.

Frequencies of the FTO rs17817449 genotypes in cases and controls and ORs (95% CIs) for ESRD by FTO genotype

	Study 1			Study 2			Pooled data
	Cases, N (%)	Controls, N (%)	OR (95% CI)	Cases, N (%)	Controls, N (%)	OR (95% CI)	Cases, N (%)	Controls, N (%)	OR (95% CI)
TT	273 (28%)	829 (33%)	1.0	350 (29%)	2204 (33%)	1.0	623 (29%)	3033 (33%)	1.0
GT	487 (49%)	1240 (50%)	1.19 (1.00–1.42)	578 (49%)	3188 (48%)	1.14 (0.99–1.32)	1065 (49%)	4428 (48%)	1.17 (1.05–1.31)
GG	224 (23%)	432 (17%)	1.56 (1.27–1.96)	260 (22%)	1289 (19%)	1.27 (1.07–1.51)	484 (22%)	1721 (19%)	1.37 (1.20–1.56)
P (chi-square)			0.0002			0.024			<0.0001
P for trend			<0.0001			0.006			<0.0001