Table 2. Putative TPAT T-components and their genomic neighbors.

Organism Name	Class	Locus Tag of Tp0956-like Protein (T)	E-valuea	Locus Tag of Nearby DctP-like Protein	Presence of DctM and/or DctQ
Treponema pallidum	Spirochaetes	tp0956	3e-99	tp0957	Yes
Treponema paraluiscuniculi	Spirochaetes	tpcca_0956	3e-99	tpcca_0957	Yes
Treponema denticola	Spirochaetes	tde1021	7e-92	tde1020	Yes
Treponema phagedenis	Spirochaetes	hmpref9554_2429	1e-87	hmpref9554_2430	Yes
Treponema vincentii	Spirochaetes	trevi0001_2396	1e-87	trevi0001_2397	Yes
Treponema primitia ZAS-2	Spirochaetes	trepr_1682	9e-85	trepr_1683	Yes
Verrucomicrobiae bacterium DG1235	Verrucomicrobiae	vdg1235_4783	2e-84	vdg1235_2234	No
Treponema azotonutricum ZAS-9	Spirochaetes	treaz_0940	3e-83	treaz_0941	Yes
Treponema brennaborense DSM 12168	Spirochaetes	trebr_1914	2e-80	trebr_1913	Yes
Alcanivorax borkumensis SK2	γ-proteobacteria	abo_0687	2e-75	abo_0688	Yes
Syntrophobacter fumaroxidans MPOB	δ-proteobacteria	sfum_2673	3e-75	sfum_2672	Yes
Spirochaeta thermophila DSM 6578	Spirochaetes	spithDRAFT_1602	3e-74	spithDRAFT_1603	Yes
Anaeromyxobacter dehalogenans 2CP-C	δ-proteobacteria	adeh_3980	3e-74	adeh_3979	Yes
Alcanivorax sp. DG881	γ-proteobacteria	adg881_3113	4e-72	adg881_421	Yes
Anaeromyxobacter sp. Fw109-5	δ-proteobacteria	anae109_0439	9e-70	anae109_0440	Yes
Anaeromyxobacter sp. K	δ-proteobacteria	anaeK_4091	4e-69	anaeK_4090	Yes
Anaeromyxobacter dehalogenans 2CP-1	δ-proteobacteria	a2cp1_4123	6e-69	a2cp1_4122	Yes
Desulfotalea psychrophila LSv54	δ-proteobacteria	dp0443	3e-68	dp0444	Yes
Spirochaeta smaragdinae DSM 11293	Spirochaetes	spirs_2251	1e-67	spirs_2250	Yes
Sideroxydans lithotrophicus ES-1	β-proteobacteria	slit_0818	5e-66	slit_0817	Yes
Dechloromonas aromatica RCB	β-proteobacteria	daro_3578	7e-65	daro_3577	Yes
Desulfuromonas acetoxidans DSM 684	δ-proteobacteria	dace_1925 dace_2628	9e-63 4e-33	dace_1924 N/A	Yes No
Desulfobacterium autotrophicum HRM2	γ-proteobacteria	hrm2_33310	2e-62	hrm2_33300	Yes
gamma proteobacterium HTCC5015	δ-proteobacteria	gp5015_96	2e-61	gp5015_80	Yes
Desulfatibacillum alkenivorans AK-01	δ-proteobacteria	dalk_2688 dalk_2187	4e-59 2e-52	N/A N/A	No Yes
Reinekea sp. MED297	γ-proteobacteria	med297_13632	3e-57	med297_13637	Yes
Desulfococcus oleovorans Hxd3	δ-proteobacteria	dole_3154 dole_3077	2e-56 8e-54	dole_3157 dole_3078, dole_3074	Yes Yes
gamma proteobacterium NOR5-3	γ-proteobacteria	nor53_2500	2e-56	nor53_2704	Yes
Methylomonas methanica MC09	γ-proteobacteria	metme_0487	2e-55	metme_0486	Yes
Thiobacillus denitrificans ATCC 25259	β-proteobacteria	tbd_0465	2e-55	tbd_0466	Yes
Leptothrix cholodnii SP-6	β-proteobacteria	lcho_3613	3e-53	lcho_3612	Yes
Spirochaeta thermophila DSM 6192	Spirochaetes	stherm_c20400	6e-50	stherm_c20410	Yes
Bacteriovorax marinus SJ	δ-proteobacteria	bms_0699	2e-44	bms_0700	Yes
Plesiocystis pacifica SIR-1	δ-proteobacteria	ppsir1_38751	1e-38	ppsir1_38741	Yes
Leptospira biflexa serovar Patoc strain ‘Patoc 1 (Paris)’	Spirochaetes	lepbi_I1477	4e-32	lepbi_I1476	Yes

^aAs defined by PSI-BLAST^{42; 67}