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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: J Pept Sci. 2011 Nov 14;18(1):1–9. doi: 10.1002/psc.1403

TABLE 1.

Name Structure Traditional
Removal Conditions
Acid-Stable Protecting Groups Bzl
R = H		 graphic file with name nihms326037t1.jpg Na/liq. NH3
(ref. 8)
Meb
R = CH3 		50% HF/Anisole
(ref. 9)
Mob
R = OCH3 		AgOTf/TFA/thioanisole
(ref. 10)
Acm graphic file with name nihms326037t2.jpg Hg(OAc)2
(ref. 11)
tBu graphic file with name nihms326037t3.jpg Hg(OTf)2
(ref. 12)
StBu graphic file with name nihms326037t4.jpg P(Ph)3
(ref. 13)
Acid-Labile Protecting Groups Trt
R = H		 graphic file with name nihms326037t5.jpg 95% TFA
(ref. 14)
Mmt
R = OCH3 		1% TFA/DCM
(ref. 15)
Xan graphic file with name nihms326037t6.jpg 1% TFA/DCM
(ref. 16)
Tmob graphic file with name nihms326037t7.jpg 7% TFA/DCM
(ref. 17)

Bzl = benzyl; Meb = 4-methylbenzyl; Mob = 4-methoxybenzyl; Acm = acetamidomethyl; tBu = tert-butyl; StBu = tert-butylmercapto-; Trt = trityl; Mmt = 4-methoxytrityl; Xan = Xanthenyl; Tmob = 2,4,6-trimethoxybenzyl