Table 2.

Multivariate logistic model for the change in the association between marijuana use and DM (total and by age group) (N=8127)

Outcome: DM	Total	Age group 41–59 years	Age group 20–40 years
Model	OR (95% CI)	OR (95% CI)	OR (95% CI)
Unadjusted	0.42 (0.33 to 0.55)*	0.51 (0.36 to 0.73)*	0.74 (0.48 to 1.14)
Model 1: adjusted for social variables	0.31 (0.20 to 0.48)*	0.34 (0.20 to 0.59)*	0.80 (0.43 to 1.50)
Model 2: adjusted for social variables and laboratory variables	0.33 (0.22 to 0.50)*	0.35 (0.21 to 0.61)*	0.87 (0.47 to 1.63)
Model 3: adjusted for social variables, laboratory variables and inflammatory marker	0.36 (0.24 to 0.54)*	0.37 (0.21 to 0.63)*	0.95 (0.50 to 1.78)
Model 4: adjusted for social variables, laboratory variables, inflammatory marker and comorbidity	0.36 (0.24 to 0.55)*	0.37 (0.22 to 0.62)*	0.93 (0.51 to 1.70)

OR for having DM among marijuana users compared to non-users and 95% CI.

Social variables: race/ethnicity, physical activity, alcohol use, interaction of alcohol and marijuana use and body mass index.

Laboratory variables: total cholesterol and triglyceride.

Inflammatory marker: C reactive protein.

Comorbidity: hypertension.

^*p<0.0001 compared to non-marijuana users.