Table 4.

Cox proportional hazards model for disease-free survival and overall survival

	Disease progression		Death
	HR (95% CI)	P	HR(95%CI)	P
Age young vs. elderly
Univariate	1.855 (1.263–2.725)	0.002	0.954 (0.605–1.505)	0.840
Multivariate	1.557 (1.035–2.3420)	0.034	0.843 (0.514–1.383)	0.499
T stage		0.189		0.099
T2 vs. T1	1.323 (0.812–2.154)	0.261	1.923 (1.017–3.636)	0.044
T3 vs. T1	1.210 (0.603–2.431)	0.592	1.255 (0.468–3.3260)	0.652
T4 vs. T1	2.537 (1.084–5.940)	0.032	2.923 (1.052–8.1220)	0.040
Lymph node status		0.000		0.000
N1 vs. N0	2.046 (1.208–3.466)	0.008	1.268 (0.815–3.253)	0.167
N2vs. N0	4.437 (2.553–7.711)	0.000	3.465 (1.720–6.978)	0.001
N3 vs. N0	6.322 (3.476–11.497)	0.000	7.259 (3.682–14.310)	0.000
ER present vs. absent	0.655 (0.378–1.134)	0.131	0.838 (0.438–1.605)	0.594
PgR present vs. absent	1.104 (0.643–1.895)	0.720	0.654 (0.347–1.231)	0.188
Her2 present vs. absent	1.584 (1.057–2.373)	0.026	1.219 (0.725–2.049)	0.455
Grade 3 vs. 1/2	1.657 (1.113–2.465)	0.013	1.456 (0.899–2.357)	0.126
Chemotherapy yes vs. no	0.842 (0.414–1.712)	0.635	0.564 (0.253–1.255)	0.161

HR = Hazard ratio; 95% CI = 95% confidence interval; ER = estrogen receptor; PgR = progesterone receptor.