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. 2011 Apr;17(4):653–660. doi: 10.3201/eid1704.101429

Table 1. Demographic characteristics and underlying conditions in 8 patients with H275Y mutation of pandemic (H1N1) 2009 virus, Seattle Cancer Care Alliance, Seattle, Washington, USA, May 1, 2009–April 30, 2010*.

Patient no. Age, y/sex BMI Underlying disease State of disease HCT Recent immunosuppressive therapy Concurrent illness Lymphocytes, × 103 cells/L
1†
51/M
20.5
AML
Remission
2 y post–allo-HCT
MMF, tacrolimus
GVHD, renal failure
110
2†
47/F
22.9
AML
Relapse
3 y post–allo-HCT
Chemotherapy 1 mo before influenza dx and 1 d after-dx
None
540
3
50/M
23.3
CML
Remission
9 mo post–allo-HCT
TBI, cyclophosphamide,
tacrolimus
GVHD
1,470
4
7/F
18.9
ALL
Relapse
NA
Chemotherapy 2 d after influenza diagnosis; prednisone 1.5 mg/kg/d
None
1,440
5
34/F
38.8
Hogkin lymphoma
Refractory
2 d pre–allo-HCT
TBI, fludarabine, cyclophosphamide
Renal failure
0
6†
17/M
19.5
ALL (T cell)
Remission
3 wk post–allo-HCT
TBI, fludarabine, cyclophosphamide,
MMF, CSA, prednisone 0.5 mg/kg/d
CMV, GVHD
154
7
17/M
22.4
Osteosarcoma
Relapse
NA
Chemotherapy 1 d before influenza diagnosis
Lung metastasis, thoracotomy, restrictive syndrome
366
8 8/F 14.5 Aplastic anemia Treatment NA ATG, CSA maintenance None 1,145

*BMI, body mass index; HCT, hemopoietic cell transplant; AML, acute myeloblastic leukemia; allo, allogenic; MMF, mycophenolate mofetil; GVHD, graft-versus-host disease; NA, not applicable; CML, chronic myeloblastic leukemia; TBI, total body irradiation; ALL, acute lymphoblastic leukemia; CSA, cyclosporine; CMV, cytomegalovirus; ATG, antithymocyte globuline.
†Patients previously reported in references (5,13).