Table 4.

Statistical Significance of Increases in Oxylipins in a sepsis murine model^a

compound	serum +/− LPS (i.p.)	Serum+/− LPS (i.n.)	serum +LPS i.p./i.n.	BALF +/− LPS (i.n.)
6 keto PGF1α	2.83	2.61	1.10	1.71
TXB2	2.37	2.18	0.92	2.47
9, 10, 13 TriHOME	3.05	0.89	0.29	9.07
PGE2	29.63	33.94	1.15	0.22
PGD2	0.63	0.25	0.39	N.D.
LTB4	N.D.b	N.D.	N.D.	82.50
12, 13 DHOME	4.85	7.64	1.58	21.26
9, 10 DHOME	6.42	11.58	1.80	5.08
14, 15 DHET	4.46	8.66	1.94	6.44
11, 12 DHET	5.41	19.85	3.67	2.92
5,6 DHET	1.71	3.83	2.24	N.D.
13 HODE	11.18	10.34	0.92	1.83
9 HODE	5.09	3.98	0.78	2.66
15 HETE	2.52	1.93	0.77	2.54
11 HETE	6.28	3.21	0.51	4.18
12 HETE	3.67	2.04	0.56	3.63
5 HETE	2.20	2.30	1.05	N.D.
12 , 13 EpOME	1.69	3.39	2.01	N.D.
9, 10 EpOME	2.71	3.58	1.32	N.D.

^aThree biological replicates were used for each group, the samples were acquired after 24 hour after LPS challenge Statistical significance was set at p=0.1. Grey= statistically significant change and White=non-significant changes. The numbers depict fold increases in individual analytes.

^bN.D. =non detect