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. Author manuscript; available in PMC: 2012 Feb 29.
Published in final edited form as: J Mol Cell Cardiol. 2009 Aug 28;47(6):835–845. doi: 10.1016/j.yjmcc.2009.08.017

Fig. 2.

Fig. 2

a, Examples of two-dimensional and M-mode echocardiography in mouse models with sham operation, MI and MI treated with AEPU or t-AUCB after three weeks of treatment showing evidence of cardiac failure with chamber dilatation in MI mice. AEPU and t-AUCB prevented the development of chamber dilatation in MI mice. b, Histologic sections (Masson’s trichrome stain) of sham-operated and MI mouse hearts, showing infarct area with scarring and gross cardiac dilatation at 3 weeks in the MI mouse. Treatment of MI mice with t-AUCB in drinking water prevented the development of cardiac remodeling. All histologic cross sections are presented with right ventricles to the right. Scale bar, 100 μm. c, Summary data for % fractional shortening (FS). Data shown are mean ± s.e.m., n = 12 for each group, *p<0.05 comparing MI and sham animals, #p<0.05 comparing treated vs. untreated MI animals.